Williams–Beuren syndrome (WS) is caused by a large deletion in one of the chromosomes 7 (7q11.23), encompassing 26–28 genes, among which is the elastin gene.1 Elastin and elastic fibers, essential for large artery structure and function, therefore become deficient and WS features hypertension in half of the patients,1 large artery stenoses, and heart disease, while the impact of WS on vessel elasticity varies with the study. Here, ELN is linked to Werner syndrome.