RB1 and esophageal cancer: As shown in Figure 10, in cultured KYSE-150 esophageal cancer cells, dose-dependent photocytotoxicities of RB and WB after irradiation using a xenon light source (21 J/cm2) were observed, with the IC50 of 1.5 μg/mL and 3.6 μg/mL, respectively.