On the other hand, we show that elevated expression of TRPC3 is associated with shortened RFS, OS, and DSS, is upregulated in N1 compared to N0 tumor cases, and tends to be enriched in the invasive tumor area; our data indicates TRCP3 may possess pro-tumorigenic potential in PAAD. This evidence concerns the gene TRPC3 and pancreatic adenocarcinoma.