Our study confirmed that ZINC000001612996, ZINC000052955754, ZINC000003978005, and ZINC000006716957 might be small molecule drugs acting as co-ligands of TRPC3 and TRPC7 by the molecular docking technique, and this result suggests that these four small molecule drugs have potential as targeted therapeutic agents for pancreatic cancer. Here, TRPC3 is linked to familial pancreatic carcinoma.