The results of univariate Cox regression suggested that eight genes were associated with recurrence in PACA patients, they were MCOLN1, PKD1, TRPC7, TRPV4, MCOLN3, TRPM1, TRPM4, and TRPC3 (Supplementary Table S1). The gene discussed is TRPM1; the disease is permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome.