TRPC7 and neoplasm: Of note, the difference in TP53 mutation frequency between high- and low-expressing tumors of TRPC3 was not observed; however, this difference was very significant between the high and low groups of TRPC7 (p = 0.86 vs. p = 0.02, respectively) further calling for investigation of the biological function of TRPC7 in the context of an existing known prominent hallmark tumor mutation in TP53 gene.