In addition, Jong Gwang Kim et al. showed that according to the multivariate survival statistics in all patients such as pathological stage, carcinoembryonic antigen (C.E.A.)marker levels, and age, the survival score in individuals with colorectal cancer with the AC/CC genotype in rs12373 was lower than the A.A. allele (rs12373A > C genotyping analysis detected that in disease-free survival (D.F.S.)with p value = 0.0008, and in overall survival (O.S.)with p value = 0.0001 in the dominant model) [21]. This evidence concerns the gene CEACAM5 and colorectal cancer.