Our study revealed that KIT, STK11, and RB1 were found mutated only in men’s tumor samples, while SMAD4, MET, and KIT were identified as altered only in blood samples from men; alterations in these genes were encountered in a large number of patients, indicating there are some differences in terms of mutations in the group of women vs. men (Figure 6). This evidence concerns the gene SMAD4 and neoplasm.