To obtain more detailed information on the potential gene functions of α-2,8 linkages to sialylation and regulatory interaction network with α-2,8 sialyltransferases, we performed a tumor marker of ST8SIA6 gene expression using high-throughput bioinformatics analysis from medical and biological data in colon cancer (Figure 8). Here, ST8SIA6 is linked to malignant colon neoplasm.