In a retrospective study of the CSF samples of patients with clinical signs of meningitis (n = 106) [34], IL-6 was studied for early differentiation between aseptic and bacterial meningitis with a cut-off value of 1418 pg/mL (95.5% sensitivity and 77.5% specificity) or 15,060 pg/mL (63.6% sensitivity and 96.7% specificity) for thediagnosis of bacterial meningitis. The gene discussed is IL6; the disease is infectious meningitis.