EMB and infection: Due to its lower expression in most pathogenic isolates, and the fact that is the major antigenic protein in the cell wall [30,32,33], it is thought to contribute to the immune response against the fungus, as it was observed by the protective effect of passive immunization with monoclonal antibodies against Gp70 during infection, causing a decreased number in the CFUs [31], and by the fact that sera from all infected patients recognize the protein [34].