AGAP3 and cutaneous mastocytosis: Table 4 presents comparisons of the demographic and clinical characteristics of patients with CM during the two study periods (2000–2010 vs. 2013–2020). The in-hospital mortality was higher during 2000–2010 (39.1%) than 2013–2000 (25.5%) (p = 0.16). Compared to those in 2013–2020, the patients with CM in 2000–2010 were significantly younger (mean age, 51 ± 19 vs. 62 ± 18; p < 0.01) and less likely to have CSF CrAg titer >1024 (21.7% vs. 34.0%, p = 0.16).