Likewise, SST0001, a 100% N-acetylated and glycol split non-anticoagulant heparin with potent anti-heparanase activity, had proved effective in reducing tumor progression and spread in multiple myeloma patients [39] and in Ewing’s sarcoma model [40], as well as in other human pediatric sarcoma models [41]. The gene discussed is HPSE; the disease is neoplasm.