In the current study, we also found that TGF-β2 caused a significant up-regulation of the most of ECMs tested and that PGF2α or OMD induced a significant up-regulation of network-forming COL4 [53] and the down-regulation of beaded-filament-forming COL6 [53], FN, and αSMA. This evidence concerns the gene ACTA1 and occult macular dystrophy.