Participants in PCOS Non-Ex had significantly lower body weight (p < 0.001), BMI (p < 0.001), systolic blood pressure (p = 0.001), HDL cholesterol (p = 0.010), insulin levels (p = 0.026), and HOMA-IR (p = 0.032) after 16 weeks compared to baseline, and there was a between-group difference in BMI compared to PCOS-HIIT (p = 0.031). This evidence concerns the gene INS and polycystic ovary syndrome.