It has been reported that caveolin-3 could regulate protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels and attenuate cardiac hypertrophy via inhibition of T-type Ca2+ current modulated by protein kinase Cα in cardiomyocytes [52,53,54]. Here, CACNA1H is linked to cardiac hypertrophy.