In a previous proteomics study conducted by our group in adult sepsis patients, we proposed a set of 10 proteins (AT-III, CLUS, SAA-1, HO-1, IL-6, IL-18, sCD25, sCD163, sICAM-1 and sFas) that can be considered as a complementary tool for the clinicians in the diagnosis of sepsis [27]. The gene discussed is IL18; the disease is Sepsis.