Likewise, mutations in the gene encoding the sodium voltage-gated channel alpha subunit 5 (SCN5A) correlated with the development of supraventricular arrhythmias (86%), sick sinus syndrome (33%), AF (60%), VT (33%), and conduction disease (60%) also in patients diagnosed with DCM [115,116]. This evidence concerns the gene SCN5A and familial dilated cardiomyopathy.