Furthermore, among women who subsequently developed HDP, we found maternal PAI-1 levels (11.11 ± 3.40 vs. 5.61 ± 2.95 pg/mL, respectively p = 0.013) and resistin levels (10.27 ± 3.31 vs. 5.09 ± 2.65 pg/mL, respectively, p = 0.012) significantly higher in the serum of patients with a pregnancy complicated by IUGR than in pregnancies without IUGR. This evidence concerns the gene SERPINE1 and fetal growth restriction.