PIGF and gestational diabetes: In our study, the best predictor for HDP in women with GDM was the sFlt-1/PIGF ratio, with an AUC of 0.814 (CI 95%: 0.66–0.98) at a concentration threshold of 3.0 pg/mL, with a sensitivity of 83.3%, a specificity of 75%, an NPV of 96.8%, a positive likelihood value (LR+) of 3.33, and a negative likelihood ratio value (LR-) of 0.22 (Figure 2).