FAS and lip and oral cavity carcinoma: The main genetic alterations affecting carcinogenesis involve changes in tumor suppressors (APC, p53 BRCA2, PTCH, NF1, VHL, Rb BCL2, SWI/SNF, p16, CD95, ST5, YPEL3, ST7, and ST14) and oncogenes (Ras, jun, fas, erbA, abl, raf, gsp, sis, erbB, and fms) in addition the onset and progression of oral cancer involve changes of DNA methylation, histone modifications, and non-coding alterations of RNA, including microRNAs (miRNA) [13,14,15,16,17,18,19,20,21].