Deguchi et al. [195] found that overexpression of PPARβ/δ was associated with the higher activation of β-catenin as well as connexin 43, eukaryotic translation initiation factor 4 gamma 1 (EIF4G1), platelet-derived growth factor receptor beta (PDGFRβ), Akt1 and cyclin-dependent kinase 1 (CDK1), which stimulated tumour (colorectal) progression. The gene discussed is CDK1; the disease is neoplasm.