Thus far, there are some parameters that have been studied for their potential use in CRC screening: e.g., carcinoembryonic antigen (CEA); cancer antigen 19-9 (CA 19-9); DNA, e.g., SMAD7 gene; proteins; messenger RNA (mRNA); microRNA (miRNA) and vascular endothelial growth factor (VEGF) family members. Here, CEACAM5 is linked to colorectal carcinoma.