ITGAM and amyotrophic lateral sclerosis: An ANOVA for repeated measurements in a mixed model confirmed the strong up-regulation of active CD11b+ CM in V2 and V3 compared to the baseline in ALS and in A-S (Figure 3D, p = 0.0011 and p < 0.0001, respectively) in contrast with the stability across time points of CD11b+CM (data not shown).