Active CD11b IM and CM monocyte subsets frequencies showed an inverse correlation with sCD11b blood concentrations both in ALS (without outliers: R = −0.44, p = 0.0038 and R = −0.41, p = 0.0073, respectively, Figure 4A) and in the ALS and NNC samples combined (without outliers: R = −0.4690, p = 0.0003 and R = −0.4386, p = 0.0009, respectively, Figure 4B). Here, ITGAM is linked to amyotrophic lateral sclerosis.