STAT3 and central nervous system cancer: The authors also reported that the expression of specific oncogenic microRNAs (miRs)—such as miR-19, miR-21, and miR-30a-5p—in glioma cell inhibition is related to an altered expression of their target genes such as STAT3, p53, EGFR, NF-κB, COX-2, and the PI3K/AKT/mTOR signaling pathway.