In addition, curcumin-induced inhibition of NF-κB signaling enhances the antitumor activity of various therapeutic agents (including the microtubule stabilizing agent paclitaxel (PTX) and the alkylating agent nimustine hydrochloride (ACNU)) against glioblastoma [67,70]. The gene discussed is NFKB1; the disease is glioblastoma.