Further, a significant increase in Iba-1 expression was also found in P. gingivalis, and HK P. gingivalis infected Tg mice (p < 0.05) (Figure 4E) 8 weeks post-infection and in P. gingivalis (p < 0.05) and HK P. gingivalis (p < 0.1) infected nTg mice (data not shown). The gene discussed is AIF1; the disease is infection.