FFAR2 and diabetes mellitus: The pro-adipogenic role of FFAR2 seems to be corroborated by studies in FFAR2 knockout mice fed a high fat diet (HFD), which then displayed lower body fat mass, improved glucose control, lower plasma FFA levels, increased energy expenditure and brown adipose tissue (BAT) density (“browning” of adipose tissue), as well as lower white adipose tissue (WAT) inflammation, suggesting FFAR2 as a crucial mediator in HFD-induced obesity/diabetes [28,72].