CAFs enhance tumor progression, invasion and migration via various mechanisms, such as expressing CXCL14, an important factor in promoting cancer growth [29], and increasing the infiltration of FOXP3+ regulatory T lymphocytes (Tregs) in the tumor site, which exerts immune suppression effect [30] and whose presence directly correlates with poor OC survival [31]. This evidence concerns the gene CXCL14 and neoplasm.