RICTOR and infection: While the σB-dependent transcription factor SpoVG is crucial for PIA production under in vitro conditions, it seems to be dispensable for PIA production of S. epidermidis under in vivo conditions, although we cannot exclude that the spoVG deletion mutant of strain 1457 might be able to produce a PIA-independent biofilm in this murine infection model, which yields in comparable CFU rates at the infection sites.