In terms of OC treatment, restoration of miR-520d-3p decreased EPHA2 protein levels, thus suppressing tumor growth and migration both in vitro and in vivo, while dual inhibition of EPHA2 in vivo using 1,2-dioleoylsn-glycero-3-phosphatidylcholine (DOPC) nanoliposomes loaded with miR-520d-3p and EPHA2-siRNA had synergistic antitumor effects and greater therapeutic efficacy than either monotherapy alone [78]. Here, EPHA2 is linked to neoplasm.