Thus, Wang et al. reported FN1, COL1A1, INHBA, and CST1 to be associated with worse overall survival in GC [9], Lu et al. found that SPP1 and FN1 were correlated with tumor relapse and poor prognosis [10], Liu et al. identified TIMP1, SPP1, CXCL8, THY1, and COL1A1 genes to be negatively correlated with survival [11], and Chong et al. found FN1, TIMP1, SPP1, APOE, and VCAN genes to be associated with poor overall survival in GC patients [12]. The gene discussed is SPP1; the disease is gastric cancer.