CD8A and relapsing-remitting multiple sclerosis: We characterized subsets of suppressive CD8+ T cells (CD8+CD122+Helios+, CD8+CD25+FoxP3+) that are altered in the common clinical forms of untreated relapsing–remitting MS (RRMS) patients, with active episodes of neurological deficit (relapses), and analyzed the associations between these subsets and demographic parameters.