In this manuscript, we have summarized how these non-coding RNAs are implicated in various aspects of ferroptosis in head and neck cancers (Table 1 and Figure 1) including iron metabolism (Mfrn1/2, LOX, TfR1, and LTF), lipid metabolism (LKB1 and ACSL4), and ROS accumulation (SLC3A2, SLC7A11, ATF3, Nrf2, and GPX4). Here, GPX4 is linked to head and neck cancer.