In this study, Gal-3 was associated with increased risk of graft failure (hazard ratios (HR) per 1 SD change, 2.12; CI95%[1.63, 2.75]; p < 0.001), more importantly for patients with hypertension (HR, 2.29; CI95%[1.80, 2.92]; p < 0.001) or smoking history (HR, 2.56; CI95%[1.95, 3.37]; p < 0.001) [95]. The gene discussed is LGALS3; the disease is Hypertension.