Alidori et al. [119] exploited ammonium-functionalized carbon nanotubes (fCNTs) (≈300 nm) in the dual-delivery of siRNAs aiming at p53 and meprin-1β, another key factor involved in AKI procedure, to proximal tubular cells specifically [120] (Figure 5c). This evidence concerns the gene TP53 and acute kidney injury.