KL and atrial fibrillation: By contrast, AF was negligible in the progeroid Klotho−/− model, accounting for 0.45 ± 0.25% and 0.38 ± 0.26% of the singlets in the B530 and YG582 channel at the stage of severe precocious aging symptoms and was not increased over control levels (0.14 ± 0.07% AF in the B530 channel, p = 0.2926; 0.14 ± 0.02% AF in the YG582 channel, p = 0.400; n = 3 both for Klotho−/− and aged-matched controls; Figure 8a,b).