Therefore, the main objective of the present research was to widen our previous study by characterizing the tissue content of a robust panel of different AMP (HBD-1-4, HNP-1-3, elafin, RNase-7, RNase-8, sPLA2, S100A7, and LL-37) in a time-lapse manner in a model of choriodecidual infection with live E. coli, which allowed us to reproduce in vitro a pathological condition, such as an ascending intrauterine infection. This evidence concerns the gene S100A7 and infection.