CPQ and neoplasm: The strong activation of the antiproliferative antibiotic actinonin, an aminopeptidase inhibitor that inhibits tumor cell growth through MAPK and WNT signaling pathways [39,40], suggests that melatonin kept granulosa cells of antral follicles in a cell growth deceleration phase by stalling mitochondrial protein synthesis and mitochondrial reticulum fragmentation [41].