IRS1 and diabetes mellitus: Finally, the two protein-coding gene features were analyzed with UniReD, using a list of 10 protein-coding genes that are known to be related to diabetes pathophysiology—SLC2A2 [45], IAPP [46], GSK [47], INSR [48], IRS1 [49], PPARG [50], KCNJ11 [51], ABCC8 [52], TCF7L2 [53] and FTO [54].