Specifically, the EA PCa (LNCaP and PC-3) and AA PCa (RC77 T/E and MDA PCa 2b) cell lines were transfected with NS or miRNA mimic/antagomir in the presence of vehicle or docetaxel treatment, then followed by caspase 3/7 activity assays to measure the apoptosis capacity. The gene discussed is CASP3; the disease is posterior cortical atrophy.