Based on our knowledge and from the search on different databases (ClinVar-NCBI”, 2020; “IARC TP53 Search”, 2020; “Search results on cosmic for H175R”, 2020), this particular mutation (H175R) we observed in our study was not reported previously in MDS or any other hematological malignancies. The gene discussed is TP53; the disease is myelodysplastic syndrome.