TAC3 and chronic kidney disease: Interestingly, when we compared among equivalent CKD subgroups of NKB and TXCI, similar ADAMTS-4 expression frequency was found in all six observed areas (NKB-CKD 1–2 vs. TXCI-CKD 1–2; NKB-CKD 3–5 vs. TXCI-CKD 3–5; all p > 0.05 for PTC, INT, PXT, DT, GC, and BW, respectively).