In paired analysis, subjects in TXCI group had significantly higher CKD stage and ci score than in TX0 group (TXCI vs. TX0, all p < 0.001, Table 2) Concordantly, significantly higher number of biopsy samples in TXCI compared to TX0 group expressed ADAMTS-4 in both observed areas of interstitial compartment (10/15 vs. 1/15, respectively; p = 0.00169 in INT, 15/15 vs. 0/15, respectively; p < 0.0001 for PTCs) and glomerular capillaries (13/15 vs. 5/15, respectively; p = 0.00778). Here, ADAMTS4 is linked to chronic kidney disease.