While several studies had established the expression of lamin B1 in several malignant tumors including prostate, renal, pancreatic, lung, gastric and hepatocellular carcinomas [23,24,25,26,27], the protein expression level of lamin B1 in breast cancer tissue relative to its expression in the normal mammary epithelium is not established. This evidence concerns the gene LMNB1 and hepatocellular carcinoma.