PIEZO1 and hereditary anemia: PIEZO1 codes for mechanically-gated ion channels with multiple roles in human organisms, mutations in this gene are comorbid with pathological conditions, namely, hereditary anemia [36], congenital lymphedema [37], lymphatic dysplasia [38], and others, implying that alterations in PIEZO1 may affect the immune response to SARS-CoV-2.