As previously reported [17,18,19,20,21,22,23,24,25,26], our data revealed that the C allele carrier of the rs1260326 variant is associated with multiple unfavorable phenotypes, such as higher systolic, diastolic, and mean BP and risk of hypertension and microalbuminuria, elevated levels of liver function indicators (such as serum ALT, AST, and γGT levels), higher total and LDL cholesterol and triglyceride and uric acid levels, as well as a higher risk of metabolic syndrome and gout. The gene discussed is GPT; the disease is hypertensive disorder.