Mutations in the CHCHD2 gene were linked to an autosomal dominant, late-onset form of PD (PARK22) in the Japanese population in 2015 by Funayama et al., who reported two missense mutations (p.T61I, p.R145Q) and a splice-site mutation (c.300+5G>A) in the CHCHD2 gene [93]. This evidence concerns the gene CHCHD2 and Parkinson disease.