Since then, several additional variants in the LRP10 have been identified in patients with PD, progressive supranuclear palsy, frontotemporal dementia, and amyotrophic lateral sclerosis, although the correlation of LRP10 variants with the development of α-synucleinopathies and other neurodegenerative diseases has been debated [104,105,106]. This evidence concerns the gene LRP10 and progressive supranuclear palsy.