As additional symptoms, one CMT2L patient with p.K141T in HSPB8 (FC031: II-1) showed scoliosis, and a 62-year-old dHMN2B woman with p.S135F in HSPB1 (FC189: IV-13) showed the most severe physical disability of being wheelchair bound (FDS: 7, CMTNSv2: 31), while a dHMN2B man with compound heterozygous HSPB1 mutations of p.R127Q and p.Y142H (FC1005: II-5) revealed late onset (45 years) and mild clinical symptoms (FDS: 1, CMTNSv2: 4) compared with other affected individuals. This evidence concerns the gene HSPB1 and scoliosis.