TPH1 and schizophrenia: Allen et al. [65] performed a meta-analysis across all ancestries comparing 829 patients with schizophrenia with 1268 controls and found that the A versus C allele at position 218 in intron 7 (rs1800532) of the TPH1 gene was associated with susceptibility to schizophrenia (OR, 1.31; 95% CI, 1.15–1.51; p-value = 0.0008).