However, it could also point out the distinct phenotypic features, illustrated by an exclusively hematological phenotype in GATA-1 DBA-like patients, compared with a multiorgan disease, encompassing congenital malformations and an increased risk to also develop solid tumors (in addition to hematological malignancies) in the case of DBA with genetic defects in genes encoding RP. The gene discussed is GATA1; the disease is Diamond-Blackfan anemia.