On the other hand, simultaneous inhibition of miR-27b-3p and LINC02381 induced the expression of CTNNB1, which in turn, enhanced the proliferation of ESCs, suggesting that the LINC02381/miR-27b-3p/CTNNB1 axis is a potential prognostic biomarker and therapeutic target for endometriosis. This evidence concerns the gene LINC02381 and endometriosis.