The DEGs DHRS9, IPCEF1, TNR, MEGF11, EDIL3, PDZD2, PDGFRA, SPOCK1, CHI3L1, FN1, IGFBP2, TNC, FCGBP, CYR61, F13A1, ANXA2 NCAM1, RPL19, SLC1A12, CNP, MT2A, CHI3L1, POSTIN, LTF, MPDZ, CPZ, LRRC32, CTNNA3, LRFN5, and SLc22A17 reported in our study are not explored by many other studies related to GBM. Here, DHRS9 is linked to glioblastoma.