BDNF and Huntington disease: Downregulation of miR-132 in HD may affect the mechanisms of the BDNF and neurogenesis due to miR-132′s targets MeCP2, which play a role in the feedback loop of BDNF expression in neurons, and p250GAP (brain-enriched NMDA receptor-interacting RhoGAP), which regulates neuronal morphogenesis [106,107].