IL17A and rheumatoid arthritis: The pathways were related to inflammatory reaction, including rheumatoid arthritis, prion diseases, phenylalanine metabolism, osteoclast differentiation, neuroactive ligand-receptor interaction, IL-17 signaling pathway, histidine metabolism, glycine, serine and threonine metabolism, estrogen signaling pathway, cholesterol metabolism, breast cancer, amoebiasis, and adrenergic signaling in cardiomyocytes (Figure 3D and Supplementary Table S5).