ADAR and autism: In the autism-related study, the authors provided experimental evidence on protein–protein interactions between FMRP-ADAR1, FMRP-ADAR2 and FXR1P-ADAR1, which directly affect RNA editing at selected transcripts, thus assigning RNA editing modulatory effects to FMRP (enhancer) and FXR1P (repressor) [45].